Wham is made for paired-conclusion Illumina libraries with typical insert dimensions (~300bp-500bp). Wham integrates mate-pair mapping, break up browse mapping, tender-clipping, alternative alignment and consensus sequence centered proof to predict SV breakpoints with solitary-nucleotide precision. Wham generates a merged pileup (catalog of reads c

Wham clusters many of the candidate breakpoints and rounds their positions to the nearest tenth foundation pair. The posture with the best browse assist is reported. In case the soft-clipped consensus sequence can be aligned to your putative breakpoint location utilizing the Smith-Waterman algorithm, the breakpoint is even further refined to The pl

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